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Subset- and Antigen-Specific Effects of Treg on CD8+ T Cell Responses in Chronic HIV Infection
We, and others, have reported that in the HIV-negative settings, regulatory CD4+CD25(high)FoxP3+ T cells (Treg) exert differential effects on CD8 subsets, and maintain the memory / effector CD8+ T cells balance, at least in part through the PD-1/PD-L1 pathway. Here we investigated Treg–mediated effe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102588/ https://www.ncbi.nlm.nih.gov/pubmed/27829019 http://dx.doi.org/10.1371/journal.ppat.1005995 |