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Subset- and Antigen-Specific Effects of Treg on CD8+ T Cell Responses in Chronic HIV Infection

We, and others, have reported that in the HIV-negative settings, regulatory CD4+CD25(high)FoxP3+ T cells (Treg) exert differential effects on CD8 subsets, and maintain the memory / effector CD8+ T cells balance, at least in part through the PD-1/PD-L1 pathway. Here we investigated Treg–mediated effe...

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Detalles Bibliográficos
Autores principales:	Nikolova, Maria, Wiedemann, Aurélie, Muhtarova, Maria, Achkova, Daniela, Lacabaratz, Christine, Lévy, Yves
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102588/ https://www.ncbi.nlm.nih.gov/pubmed/27829019 http://dx.doi.org/10.1371/journal.ppat.1005995

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