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The Role of TLR4 on B Cell Activation and Anti-β (2)GPI Antibody Production in the Antiphospholipid Syndrome

High titer of anti-β (2)-glycoprotein I antibodies (anti-β (2)GPI Ab) plays a pathogenic role in antiphospholipid syndrome (APS). Numerous studies have focused on the pathological mechanism in APS; however, little attention is paid to the immune mechanism of production of anti-β (2)GPI antibodies in...

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Detalles Bibliográficos
Autores principales: Cheng, Si, Wang, Haibo, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102736/
https://www.ncbi.nlm.nih.gov/pubmed/27868072
http://dx.doi.org/10.1155/2016/1719720