Cargando…

Plasma Membrane Targeting of Protocadherin 15 Is Regulated by the Golgi-Associated Chaperone Protein PIST

Protocadherin 15 (PCDH15) is a core component of hair cell tip-links and crucial for proper function of inner ear hair cells. Mutations of PCDH15 gene cause syndromic and nonsyndromic hearing loss. At present, the regulatory mechanisms responsible for the intracellular transportation of PCDH15 large...

Descripción completa

Detalles Bibliográficos
Autores principales: Nie, Hongyun, Liu, Yueyue, Yin, Xiaolei, Cao, Huiren, Wang, Yanfei, Xiong, Wei, Lin, Yushuang, Xu, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102745/
https://www.ncbi.nlm.nih.gov/pubmed/27867666
http://dx.doi.org/10.1155/2016/8580675