The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment

Amplification and over expression of erbB2/neu proto-oncogene is observed in 20–30% human breast cancer and is inversely correlated with the survival of the patient. Despite this, somatic activating mutations within erbB2 in human breast cancers are rare. However, we have previously reported that a...

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Detalles Bibliográficos
Autores principales: Turpin, Jason, Ling, Chen, Crosby, Erika J., Hartmann, Zachary C., Simond, Alexandra M., Chodosh, Lewis A., Rennhack, Jonathan P., Andrechek, Eran R., Ozcelik, John, Hallett, Michael, Mills, Gordon B., Cardiff, Robert D., Gray, Joe W., Griffith, Obi L., Muller, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102823/
https://www.ncbi.nlm.nih.gov/pubmed/27157621
http://dx.doi.org/10.1038/onc.2016.129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102823/
https://www.ncbi.nlm.nih.gov/pubmed/27157621
http://dx.doi.org/10.1038/onc.2016.129

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