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Validation of a Rapid, Robust, Inexpensive Screening Method for Detecting the HLA-B(*)58:01 Allele in the Prevention of Allopurinol-Induced Severe Cutaneous Adverse Reactions
The HLA B(*)58:01 allele has been worldwide reported as a pharmacogenetic susceptibility to allopurinol-induced severe cutaneous adverse reactions (SCARs). To prevent these life-threatening conditions, the American College of Rheumatology hingly recommended that the HLA-B(*)58:01 be screened prior t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102839/ https://www.ncbi.nlm.nih.gov/pubmed/27826965 http://dx.doi.org/10.4168/aair.2017.9.1.79 |