Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF

Subversion of the host immune system by viruses is often mediated by molecular decoys that sequester host proteins pivotal to mounting effective immune responses. The widespread mammalian pathogen parapox Orf virus deploys GIF, a member of the poxvirus immune evasion superfamily, to antagonize GM-CS...

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Detalles Bibliográficos
Autores principales: Felix, Jan, Kandiah, Eaazhisai, De Munck, Steven, Bloch, Yehudi, van Zundert, Gydo C.P., Pauwels, Kris, Dansercoer, Ann, Novanska, Katka, Read, Randy J., Bonvin, Alexandre M.J.J., Vergauwen, Bjorn, Verstraete, Kenneth, Gutsche, Irina, Savvides, Savvas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103067/
https://www.ncbi.nlm.nih.gov/pubmed/27819269
http://dx.doi.org/10.1038/ncomms13228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103067/
https://www.ncbi.nlm.nih.gov/pubmed/27819269
http://dx.doi.org/10.1038/ncomms13228

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