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Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission

GABA(A) receptors (GABA(A)Rs) mediate the majority of fast inhibitory neurotransmission in the brain via synergistic association with the postsynaptic scaffolding protein gephyrin and its interaction partners. However, unlike their counterparts at glutamatergic synapses, gephyrin and its binding par...

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Detalles Bibliográficos
Autores principales: Ghosh, Himanish, Auguadri, Luca, Battaglia, Sereina, Simone Thirouin, Zahra, Zemoura, Khaled, Messner, Simon, Acuña, Mario A., Wildner, Hendrik, Yévenes, Gonzalo E., Dieter, Andrea, Kawasaki, Hiroshi, O. Hottiger, Michael, Zeilhofer, Hanns Ulrich, Fritschy, Jean-Marc, Tyagarajan, Shiva K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103071/
https://www.ncbi.nlm.nih.gov/pubmed/27819299
http://dx.doi.org/10.1038/ncomms13365