Fucose-containing fraction of Ling-Zhi enhances lipid rafts-dependent ubiquitination of TGFβ receptor degradation and attenuates breast cancer tumorigenesis

Ganoderma lucidum exerts antitumor activity, but the mechanism of G. lucidum polysaccharides on cancer is unclear. Here, we demonstrated that a fucose-containing fraction of Ling-Zhi (FFLZ) reduced tumor size and suppressed metastasis in vivo. Furthermore, FFLZ inhibited breast cancer cell migration...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsao, Shu-Ming, Hsu, Hsien-Yeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103195/
https://www.ncbi.nlm.nih.gov/pubmed/27830743
http://dx.doi.org/10.1038/srep36563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103195/
https://www.ncbi.nlm.nih.gov/pubmed/27830743
http://dx.doi.org/10.1038/srep36563

Ejemplares similares