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Activation of AMPKα mediates additive effects of solamargine and metformin on suppressing MUC1 expression in castration-resistant prostate cancer cells

Prostate cancer is the second most common cause of cancer-related deaths worldwide. The mucin 1 (MUC1) oncoprotein is highly expressed in human prostate cancers with aggressive features. However, the role for MUC1 in occurrence and progression of castration-resistant prostate cancer (CRPC) remained...

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Detalles Bibliográficos
Autores principales: Xiang, SongTao, Zhang, QiuHong, Tang, Qing, Zheng, Fang, Wu, JingJing, Yang, LiJun, Hann, Swei Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103223/
https://www.ncbi.nlm.nih.gov/pubmed/27830724
http://dx.doi.org/10.1038/srep36721