Noscapine targets EGFR(p-Tyr1068) to suppress the proliferation and invasion of MG63 cells

Osteosarcoma, the most common primary malignant bone tumor, usually arises in the metaphysis of long bones. Amplification and mutation of the epidermal growth factor receptor (EGFR) gene represent signature genetic abnormalities encountered in osteosarcoma. Noscapine is a benzylisoquinoline alkaloid...

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Detalles Bibliográficos
Autores principales: He, Ming, Jiang, Linlin, Ren, Zhaozhou, Wang, Guangbin, Wang, Jiashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103267/
https://www.ncbi.nlm.nih.gov/pubmed/27830833
http://dx.doi.org/10.1038/srep37062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103267/
https://www.ncbi.nlm.nih.gov/pubmed/27830833
http://dx.doi.org/10.1038/srep37062

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