Molecular Mechanism and Energy Basis of Conformational Diversity of Antibody SPE7 Revealed by Molecular Dynamics Simulation and Principal Component Analysis

More and more researchers are interested in and focused on how a limited repertoire of antibodies can bind and correspondingly protect against an almost limitless diversity of invading antigens. In this work, a series of 200-ns molecular dynamics (MD) simulations followed by principal component (PC)...

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Detalles Bibliográficos
Autores principales: Chen, Jianzhong, Wang, Jinan, Zhu, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103278/
https://www.ncbi.nlm.nih.gov/pubmed/27830740
http://dx.doi.org/10.1038/srep36900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103278/
https://www.ncbi.nlm.nih.gov/pubmed/27830740
http://dx.doi.org/10.1038/srep36900

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