Marked increases in mucociliary clearance produced by synergistic secretory agonists or inhibition of the epithelial sodium channel

Mucociliary clearance (MCC) is a critical host innate defense mechanism in airways, and it is impaired in cystic fibrosis (CF) and other obstructive lung diseases. Epithelial fluid secretion and absorption modify MCC velocity (MCCV). We tested the hypotheses that inhibiting fluid absorption accelera...

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Detalles Bibliográficos
Autores principales: Joo, Nam Soo, Jeong, Jin Hyeok, Cho, Hyung-Ju, Wine, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103292/
https://www.ncbi.nlm.nih.gov/pubmed/27830759
http://dx.doi.org/10.1038/srep36806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103292/
https://www.ncbi.nlm.nih.gov/pubmed/27830759
http://dx.doi.org/10.1038/srep36806

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