Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
Autophagy is considered primarily a cell survival process, although it can also lead to cell death. However, the factors that dictate the shift between these 2 opposite outcomes remain largely unknown. In this work, we used Δ(9)-tetrahydrocannabinol (THC, the main active component of marijuana, a co...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103338/ https://www.ncbi.nlm.nih.gov/pubmed/27635674 http://dx.doi.org/10.1080/15548627.2016.1213927 |