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Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase

Ehrlichia chaffeensis is an obligatory intracellular bacterium that causes a potentially fatal emerging zoonosis, human monocytic ehrlichiosis. E. chaffeensis has a limited capacity for biosynthesis and metabolism and thus depends mostly on host-synthesized nutrients for growth. Although the host ce...

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Detalles Bibliográficos
Autores principales: Lin, Mingqun, Liu, Hongyan, Xiong, Qingming, Niu, Hua, Cheng, Zhihui, Yamamoto, Akitsugu, Rikihisa, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103349/
https://www.ncbi.nlm.nih.gov/pubmed/27541856
http://dx.doi.org/10.1080/15548627.2016.1217369