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Disease gene prioritization by integrating tissue-specific molecular networks using a robust multi-network model

BACKGROUND: Accurately prioritizing candidate disease genes is an important and challenging problem. Various network-based methods have been developed to predict potential disease genes by utilizing the disease similarity network and molecular networks such as protein interaction or gene co-expressi...

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Detalles Bibliográficos
Autores principales: Ni, Jingchao, Koyuturk, Mehmet, Tong, Hanghang, Haines, Jonathan, Xu, Rong, Zhang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103411/
https://www.ncbi.nlm.nih.gov/pubmed/27829360
http://dx.doi.org/10.1186/s12859-016-1317-x