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TfAP-2 is required for night sleep in Drosophila

BACKGROUND: The AP-2 transcription factor APTF-1 is crucially required for developmentally controlled sleep behavior in Caenorhabditis elegans larvae. Its human ortholog, TFAP-2beta, causes Char disease and has also been linked to sleep disorders. These data suggest that AP-2 transcription factors m...

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Detalles Bibliográficos
Autores principales: Kucherenko, Mariya M., Ilangovan, Vinodh, Herzig, Bettina, Shcherbata, Halyna R., Bringmann, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103423/
https://www.ncbi.nlm.nih.gov/pubmed/27829368
http://dx.doi.org/10.1186/s12868-016-0306-3