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Short tandem repeats, segmental duplications, gene deletion, and genomic instability in a rapidly diversified immune gene family

BACKGROUND: Genomic regions with repetitive sequences are considered unstable and prone to swift DNA diversification processes. A highly diverse immune gene family of the sea urchin (Strongylocentrotus purpuratus), called Sp185/333, is composed of clustered genes with similar sequence as well as sev...

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Detalles Bibliográficos
Autores principales: Oren, Matan, Barela Hudgell, Megan A., D’Allura, Brian, Agronin, Jacob, Gross, Alexandra, Podini, Daniele, Smith, L. Courtney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103432/
https://www.ncbi.nlm.nih.gov/pubmed/27829352
http://dx.doi.org/10.1186/s12864-016-3241-x