WRN-targeted therapy using inhibitors NSC 19630 and NSC 617145 induce apoptosis in HTLV-1-transformed adult T-cell leukemia cells

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) infection is associated with adult T-cell leukemia/lymphoma (ATLL), a lymphoproliferative malignancy with a dismal prognosis and limited therapeutic options. Recent evidence shows that HTLV-1-transformed cells present defects in both DNA replic...

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Detalles Bibliográficos
Autores principales: Moles, R., Bai, X. T., Chaib-Mezrag, H., Nicot, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103433/
https://www.ncbi.nlm.nih.gov/pubmed/27829440
http://dx.doi.org/10.1186/s13045-016-0352-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103433/
https://www.ncbi.nlm.nih.gov/pubmed/27829440
http://dx.doi.org/10.1186/s13045-016-0352-4

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