Administration of JTE013 abrogates experimental asthma by regulating proinflammatory cytokine production from bronchial epithelial cells

BACKGROUND: Sphingosine-1-phosphate (S1P) is a bioactive phospholipid that acts as a signal transducer by binding to S1P receptors (S1PR) 1 to 5. The S1P/S1PRs pathway has been associated with remodeling and allergic inflammation in asthma, but the expression pattern of S1PR and its effects on non-i...

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Detalles Bibliográficos
Autores principales: Terashita, Tomomi, Kobayashi, Kazuyuki, Nagano, Tatsuya, Kawa, Yoshitaka, Tamura, Daisuke, Nakata, Kyosuke, Yamamoto, Masatsugu, Tachihara, Motoko, Kamiryo, Hiroshi, Nishimura, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103479/
https://www.ncbi.nlm.nih.gov/pubmed/27829417
http://dx.doi.org/10.1186/s12931-016-0465-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103479/
https://www.ncbi.nlm.nih.gov/pubmed/27829417
http://dx.doi.org/10.1186/s12931-016-0465-x

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