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Pyruvate oxidase of Streptococcus pneumoniae contributes to pneumolysin release

BACKGROUND: Streptococcus pneumoniae is one of the leading causes of community acquired pneumonia and acute otitis media. Certain aspects of S. pneumoniae’s virulence are dependent upon expression and release of the protein toxin pneumolysin (PLY) and upon the activity of the peroxide-producing enzy...

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Detalles Bibliográficos
Autores principales: Bryant, Joseph C., Dabbs, Ridge C., Oswalt, Katie L., Brown, Lindsey R., Rosch, Jason W., Seo, Keun S., Donaldson, Janet R., McDaniel, Larry S., Thornton, Justin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103497/
https://www.ncbi.nlm.nih.gov/pubmed/27829373
http://dx.doi.org/10.1186/s12866-016-0881-6