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Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss

BACKGROUND: Increased reactive oxygen species and estrogen deficiency contribute to the pathophysiology of postmenopausal osteoporosis. Reactive oxygen species contribute to bone degradation and is necessary for RANKL-induced osteoclast differentiation. In postmenopausal bone loss, reactive oxygen s...

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Detalles Bibliográficos
Autores principales: Stubelius, Alexandra, Andersson, Annica, Holmdahl, Rikard, Ohlsson, Claes, Islander, Ulrika, Carlsten, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103594/
https://www.ncbi.nlm.nih.gov/pubmed/27829407
http://dx.doi.org/10.1186/s12891-016-1315-1