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Effects of Aggregatibacter actinomycetemcomitans leukotoxin on neutrophil migration and extracellular trap formation

BACKGROUND: Aggressive periodontitis is associated with the presence of Aggregatibacter actinomycetemcomitans, a leukotoxin (Ltx)-producing periodontal pathogen. Ltx has the ability to lyse white blood cells including neutrophils. OBJECTIVES: This study was aimed at investigating the interactions be...

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Detalles Bibliográficos
Autores principales: Hirschfeld, Josefine, Roberts, Helen M., Chapple, Iain L. C., Parčina, Marijo, Jepsen, Søren, Johansson, Anders, Claesson, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103672/
https://www.ncbi.nlm.nih.gov/pubmed/27834173
http://dx.doi.org/10.3402/jom.v8.33070