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Potential protective effects of autophagy activated in MPP+ treated astrocytes

Astrocytes, which have various important functions, have previously been associated with Parkinsons disease (PD), particularly in 1-methyl-4-phenylpyridinium (MPP+) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) models of PD. MPP+ is the toxic metabolite of MPTP and is generated by the enzy...

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Detalles Bibliográficos
Autores principales: Shen, Cunzhou, Xian, Wenbiao, Zhou, Hongyan, Chen, Ling, Pei, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103691/
https://www.ncbi.nlm.nih.gov/pubmed/27882077
http://dx.doi.org/10.3892/etm.2016.3736