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Iron overload induced death of osteoblasts in vitro: involvement of the mitochondrial apoptotic pathway

BACKGROUND: Iron overload is recognized as a new pathogenfor osteoporosis. Various studies demonstrated that iron overload could induce apoptosis in osteoblasts and osteoporosis in vivo. However, the exact molecular mechanisms involved in the iron overload-mediated induction of apoptosis in osteobla...

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Detalles Bibliográficos
Autores principales: Tian, Qing, Wu, Shilei, Dai, Zhipeng, Yang, Jingjing, Zheng, Jin, Zheng, Qixin, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103817/
https://www.ncbi.nlm.nih.gov/pubmed/27843711
http://dx.doi.org/10.7717/peerj.2611