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Deconvoluting simulated metagenomes: the performance of hard- and soft- clustering algorithms applied to metagenomic chromosome conformation capture (3C)
BACKGROUND: Chromosome conformation capture, coupled with high throughput DNA sequencing in protocols like Hi-C and 3C-seq, has been proposed as a viable means of generating data to resolve the genomes of microorganisms living in naturally occuring environments. Metagenomic Hi-C and 3C-seq datasets...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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PeerJ Inc.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103821/ https://www.ncbi.nlm.nih.gov/pubmed/27843713 http://dx.doi.org/10.7717/peerj.2676 |