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Heteroplasmy of mutant mitochondrial DNA A10398G and analysis of its prognostic value in non-small cell lung cancer

Mitochondrial dysfunction is associated with pathogenic mitochondrial (mt)DNA mutations. The majority of mtDNA point mutations have a heteroplasmic status, which is defined as the coexistence of wild-type and mutated DNA within a cell or tissue. Previous findings demonstrated that certain mtDNA hete...

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Detalles Bibliográficos
Autores principales: Qi, Yuexiao, Wei, Yuehua, Wang, Qiaoli, Xu, Hui, Wang, You, Yao, Anqi, Yang, Hui, Gao, Yan, Zhou, Fuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103904/
https://www.ncbi.nlm.nih.gov/pubmed/27899967
http://dx.doi.org/10.3892/ol.2016.5086