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The targetable role of herpes virus-associated ubiquitin-specific protease (HAUSP) in p190 BCR-ABL leukemia

Philadelphia chromosome-positive (Ph(+)) acute lymphoblastic leukemia (ALL) is driven by the p190 breakpoint cluster region (BCR)-ABL isoform. Although effectively targeted by BCR-ABL tyrosine kinase inhibitors (TKIs), ALL is associated with a less effective response to TKIs compared with chronic my...

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Detalles Bibliográficos
Autores principales: Carrà, Giovanna, Panuzzo, Cristina, Crivellaro, Sabrina, Morena, Deborah, Taulli, Riccardo, Guerrasio, Angelo, Saglio, Giuseppe, Morotti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103907/
https://www.ncbi.nlm.nih.gov/pubmed/27899971
http://dx.doi.org/10.3892/ol.2016.5073