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Possible role of thymidine phosphorylase in gynecological tumors as an individualized treatment strategy

Thymidine phosphorylase (TP) is structurally similar to platelet-derived endothelial cell growth factor, and it activates 5-fluorouracil (5-FU) prodrugs and also promotes angiogenesis. In the present study, the possibility of using TP expression as a biomarker for 5-FU prodrugs, and the significance...

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Detalles Bibliográficos
Autores principales: Shida, Masako, Yasuda, Masanori, Fujita, Mariko, Miyazawa, Masaki, Kajiwara, Hiroshi, Hirasawa, Takeshi, Ikeda, Masae, Matsui, Naruaki, Muramatsu, Toshinari, Mikami, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103922/
https://www.ncbi.nlm.nih.gov/pubmed/27899985
http://dx.doi.org/10.3892/ol.2016.5082