Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases

The efficacy of angiogenesis inhibitors in cancer is limited by resistance mechanisms that are poorly understood. Notably, instead of inducing angiogenesis, some cancers vascularize by the non-angiogenic mechanism of vessel co-option. Here we show that vessel co-option is associated with a poor resp...

Descripción completa

Detalles Bibliográficos
Autores principales: Frentzas, Sophia, Simoneau, Eve, Bridgeman, Victoria L., Vermeulen, Peter B., Foo, Shane, Kostaras, Eleftherios, Nathan, Mark, Wotherspoon, Andrew, Gao, Zu-hua, Shi, Yu, Van den Eynden, Gert, Daley, Frances, Peckitt, Clare, Tan, Xianming, Salman, Ayat, Lazaris, Anthoula, Gazinska, Patrycja, Berg, Tracy J., Eltahir, Zak, Ritsma, Laila, Van Rheenen, Jacco, Khashper, Alla, Brown, Gina, Nystrom, Hanna, Sund, Malin, Van Laere, Steven, Loyer, Evelyne, Dirix, Luc, Cunningham, David, Metrakos, Peter, Reynolds, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104270/
https://www.ncbi.nlm.nih.gov/pubmed/27748747
http://dx.doi.org/10.1038/nm.4197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104270/
https://www.ncbi.nlm.nih.gov/pubmed/27748747
http://dx.doi.org/10.1038/nm.4197

Ejemplares similares