Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials

OBJECTIVE: To compare efficacy, safety, and tolerability of an oral enzyme combination (OEC) containing proteolytic enzymes and bioflavonoid vs diclofenac (DIC), a nonselective nonsteroidal anti-inflammatory drug in the treatment of osteoarthritis of the knee. MATERIALS AND METHODS: This was an indi...

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Detalles Bibliográficos
Autores principales: Ueberall, Michael A, Mueller-Schwefe, Gerhard HH, Wigand, Rainer, Essner, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104298/
https://www.ncbi.nlm.nih.gov/pubmed/27853388
http://dx.doi.org/10.2147/JPR.S108563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104298/
https://www.ncbi.nlm.nih.gov/pubmed/27853388
http://dx.doi.org/10.2147/JPR.S108563

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