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Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials

OBJECTIVE: To compare efficacy, safety, and tolerability of an oral enzyme combination (OEC) containing proteolytic enzymes and bioflavonoid vs diclofenac (DIC), a nonselective nonsteroidal anti-inflammatory drug in the treatment of osteoarthritis of the knee. MATERIALS AND METHODS: This was an indi...

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Detalles Bibliográficos
Autores principales:	Ueberall, Michael A, Mueller-Schwefe, Gerhard HH, Wigand, Rainer, Essner, Ute
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104298/ https://www.ncbi.nlm.nih.gov/pubmed/27853388 http://dx.doi.org/10.2147/JPR.S108563

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