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Animal models of β-hemoglobinopathies: utility and limitations

The structural and functional conservation of hemoglobin throughout mammals has made the laboratory mouse an exceptionally useful organism in which to study both the protein and the individual globin genes. Early researchers looked to the globin genes as an excellent model in which to examine gene r...

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Detalles Bibliográficos
Autores principales: McColl, Bradley, Vadolas, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104300/
https://www.ncbi.nlm.nih.gov/pubmed/27853395
http://dx.doi.org/10.2147/JBM.S87955