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Development of novel HER2 inhibitors against gastric cancer derived from flavonoid source of Syzygium alternifolium through molecular dynamics and pharmacophore-based screening

Continuous usage of synthetic chemotherapeutic drugs causes adverse effects, which prompted for the development of alternative therapeutics for gastric cancer from natural source. This study was carried out with a specific aim to screen gastroprotective compounds from the fruits of Syzygium alternif...

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Detalles Bibliográficos
Autores principales: Babu, Tirumalasetty Muni Chandra, Rammohan, Aluru, Baki, Vijaya Bhaskar, Devi, Savita, Gunasekar, Duvvuru, Rajendra, Wudayagiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104305/
https://www.ncbi.nlm.nih.gov/pubmed/27853354
http://dx.doi.org/10.2147/DDDT.S111914