Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial

BACKGROUND: COPD patients have high pulmonary and systemic oxidative stress that correlates with severity of disease. Sulforaphane has been shown to induce expression of antioxidant genes via activation of a transcription factor, nuclear factor erythroid-2 related factor 2 (Nrf2). METHODS: This para...

Descripción completa

Detalles Bibliográficos
Autores principales: Wise, Robert A., Holbrook, Janet T., Criner, Gerard, Sethi, Sanjay, Rayapudi, Sobharani, Sudini, Kuladeep R., Sugar, Elizabeth A., Burke, Alyce, Thimmulappa, Rajesh, Singh, Anju, Talalay, Paul, Fahey, Jed W., Berenson, Charles S., Jacobs, Michael R., Biswal, Shyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104323/
https://www.ncbi.nlm.nih.gov/pubmed/27832073
http://dx.doi.org/10.1371/journal.pone.0163716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104323/
https://www.ncbi.nlm.nih.gov/pubmed/27832073
http://dx.doi.org/10.1371/journal.pone.0163716

Ejemplares similares