Enhanced Detection of Low-Abundance Human Plasma Proteins by Integrating Polyethylene Glycol Fractionation and Immunoaffinity Depletion

The enormous depth complexity of the human plasma proteome poses a significant challenge for current mass spectrometry-based proteomic technologies in terms of detecting low-level proteins in plasma, which is essential for successful biomarker discovery efforts. Typically, a single-step analytical a...

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Detalles Bibliográficos
Autores principales: Liu, Zhao, Fan, Songhua, Liu, Haipeng, Yu, Jia, Qiao, Rui, Zhou, Mi, Yang, Yongtao, Zhou, Jian, Xie, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104378/
https://www.ncbi.nlm.nih.gov/pubmed/27832179
http://dx.doi.org/10.1371/journal.pone.0166306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104378/
https://www.ncbi.nlm.nih.gov/pubmed/27832179
http://dx.doi.org/10.1371/journal.pone.0166306

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