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Progression Rate From Intermediate to Advanced Age-Related Macular Degeneration Is Correlated With the Number of Risk Alleles at the CFH Locus

PURPOSE: Progression rate of age-related macular degeneration (AMD) varies substantially, yet its association with genetic variation has not been widely examined. METHODS: We tested whether progression rate from intermediate AMD to geographic atrophy (GA) or choroidal neovascularization (CNV) was co...

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Detalles Bibliográficos
Autores principales: Sardell, Rebecca J., Persad, Patrice J., Pan, Samuel S., Whitehead, Patrice, Adams, Larry D., Laux, Reneé A., Fortun, Jorge A., Brantley, Milam A., Kovach, Jaclyn L., Schwartz, Stephen G., Agarwal, Anita, Haines, Jonathan L., Scott, William K., Pericak-Vance, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104418/
https://www.ncbi.nlm.nih.gov/pubmed/27832277
http://dx.doi.org/10.1167/iovs.16-19519