Regioselective Glucuronidation of Diosmetin and Chrysoeriol by the Interplay of Glucuronidation and Transport in UGT1A9-Overexpressing HeLa Cells

This study aimed to determine the reaction kinetics of the regioselective glucuronidation of diosmetin and chrysoeriol, two important methylated metabolites of luteolin, by human liver microsomes (HLMs) and uridine-5′-diphosphate glucuronosyltransferase (UGTs) enzymes. This study also investigated t...

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Detalles Bibliográficos
Autores principales: Zeng, Xuejun, Shi, Jian, Zhao, Min, Chen, Qingwei, Wang, Liping, Jiang, Huangyu, Luo, Feifei, Zhu, Lijun, Lu, Linlin, Wang, Xinchun, Liu, Zhongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104480/
https://www.ncbi.nlm.nih.gov/pubmed/27832172
http://dx.doi.org/10.1371/journal.pone.0166239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104480/
https://www.ncbi.nlm.nih.gov/pubmed/27832172
http://dx.doi.org/10.1371/journal.pone.0166239

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