Cargando…

Increasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis

Mechanical force and Wnt signaling activate β-catenin-mediated transcription to promote proliferation and tissue expansion. However, it is unknown whether mechanical force and Wnt signaling act independently or synergize to activate β-catenin signaling and cell division. We show that mechanical stra...

Descripción completa

Detalles Bibliográficos
Autores principales: Benham-Pyle, Blair W, Sim, Joo Yong, Hart, Kevin C, Pruitt, Beth L, Nelson, William James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104517/
https://www.ncbi.nlm.nih.gov/pubmed/27782880
http://dx.doi.org/10.7554/eLife.19799