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Increasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis
Mechanical force and Wnt signaling activate β-catenin-mediated transcription to promote proliferation and tissue expansion. However, it is unknown whether mechanical force and Wnt signaling act independently or synergize to activate β-catenin signaling and cell division. We show that mechanical stra...
Autores principales: | Benham-Pyle, Blair W, Sim, Joo Yong, Hart, Kevin C, Pruitt, Beth L, Nelson, William James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104517/ https://www.ncbi.nlm.nih.gov/pubmed/27782880 http://dx.doi.org/10.7554/eLife.19799 |
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