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Crystal Structure of the Neuropilin-1 MAM Domain: Completing the Neuropilin-1 Ectodomain Picture

Neuropilins (NRPs) are single-pass transmembrane receptors involved in several signaling pathways that regulate key physiological processes such as vascular morphogenesis and axon guidance. The MAM domain of NRP, which has previously been implicated in receptor multimerization, was the only portion...

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Detalles Bibliográficos
Autores principales: Yelland, Tamas, Djordjevic, Snezana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104691/
https://www.ncbi.nlm.nih.gov/pubmed/27720589
http://dx.doi.org/10.1016/j.str.2016.08.017