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Immunological and Translational Aspects of NK Cell-Based Antitumor Immunotherapies
Natural killer (NK) cells play a pivotal role in the first line of defense against cancer. NK cells that are deficient in CD3 and a clonal T cell receptor (TCR) can be subdivided into two major subtypes, CD56(dim)CD16(+) cytotoxic and CD56(bright)CD16(−) immunoregulatory NK cells. Cytotoxic NK cells...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104957/ https://www.ncbi.nlm.nih.gov/pubmed/27891129 http://dx.doi.org/10.3389/fimmu.2016.00492 |