Inflammatory cytokine IL6 cooperates with CUDR to aggravate hepatocyte-like stem cells malignant transformation through NF-κB signaling

Inflammatory cytokines and lncRNAs are closely associated with tumorigenesis. Herein, we reveal inflammatory cytokines IL6 cooperates with long noncoding RNA CUDR to trigger the malignant transformation of human embryonic stem cells-derived hepatocyte-like stem cells. Mechanistically, IL6 cooperates...

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Detalles Bibliográficos
Autores principales: Zheng, Qidi, Lin, Zhuojia, Li, Xiaonan, Xin, Xiaoru, Wu, Mengying, An, Jiahui, Gui, Xin, Li, Tianming, Pu, Hu, Li, Haiyan, Lu, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104983/
https://www.ncbi.nlm.nih.gov/pubmed/27833137
http://dx.doi.org/10.1038/srep36843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104983/
https://www.ncbi.nlm.nih.gov/pubmed/27833137
http://dx.doi.org/10.1038/srep36843

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