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Inflammatory cytokine IL6 cooperates with CUDR to aggravate hepatocyte-like stem cells malignant transformation through NF-κB signaling
Inflammatory cytokines and lncRNAs are closely associated with tumorigenesis. Herein, we reveal inflammatory cytokines IL6 cooperates with long noncoding RNA CUDR to trigger the malignant transformation of human embryonic stem cells-derived hepatocyte-like stem cells. Mechanistically, IL6 cooperates...
Autores principales: | Zheng, Qidi, Lin, Zhuojia, Li, Xiaonan, Xin, Xiaoru, Wu, Mengying, An, Jiahui, Gui, Xin, Li, Tianming, Pu, Hu, Li, Haiyan, Lu, Dongdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104983/ https://www.ncbi.nlm.nih.gov/pubmed/27833137 http://dx.doi.org/10.1038/srep36843 |
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