Molecular inotropy mediated by cardiac miR-based PDE4D/PRKAR1α/phosphoprotein signaling

Molecular inotropy refers to cardiac contractility that can be modified to affect overall heart pump performance. Here we show evidence of a new molecular pathway for positive inotropy by a cardiac-restricted microRNA (miR). We report enhanced cardiac myocyte performance by acute titration of cardia...

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Detalles Bibliográficos
Autores principales: Bedada, Fikru B., Martindale, Joshua J., Arden, Erik, Metzger, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105063/
https://www.ncbi.nlm.nih.gov/pubmed/27833092
http://dx.doi.org/10.1038/srep36803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105063/
https://www.ncbi.nlm.nih.gov/pubmed/27833092
http://dx.doi.org/10.1038/srep36803

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