Cargando…
Molecular inotropy mediated by cardiac miR-based PDE4D/PRKAR1α/phosphoprotein signaling
Molecular inotropy refers to cardiac contractility that can be modified to affect overall heart pump performance. Here we show evidence of a new molecular pathway for positive inotropy by a cardiac-restricted microRNA (miR). We report enhanced cardiac myocyte performance by acute titration of cardia...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105063/ https://www.ncbi.nlm.nih.gov/pubmed/27833092 http://dx.doi.org/10.1038/srep36803 |