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Photothermal therapy improves the efficacy of a MEK inhibitor in neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive tumors with low survival rates and the leading cause of death in neurofibromatosis type 1 (NF1) patients under 40 years old. Surgical resection is the standard of care for MPNSTs, but is often incomplete and can generate loss of functi...

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Detalles Bibliográficos
Autores principales: Sweeney, Elizabeth E., Burga, Rachel A., Li, Chaoyang, Zhu, Yuan, Fernandes, Rohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105126/
https://www.ncbi.nlm.nih.gov/pubmed/27833160
http://dx.doi.org/10.1038/srep37035