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Utility and limitations of multiplex ligation-dependent probe amplification technique in the detection of cytogenetic abnormalities in products of conception

BACKGROUND AND INTRODUCTION: Chromosomal abnormality is found in about half of first-trimester abortions. Karyotype is the gold standard to detect chromosomal abnormalities. Multiplex ligation-dependent probe amplification (MLPA) offers advantage over karyotype in terms of lower failure rate, faster...

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Detalles Bibliográficos
Autores principales: Saxena, D, Agarwal, M, Gupta, D, Agrawal, S, Das, V, Phadke, SR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105209/
https://www.ncbi.nlm.nih.gov/pubmed/27763481
http://dx.doi.org/10.4103/0022-3859.192664