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DRABAL: novel method to mine large high-throughput screening assays using Bayesian active learning

BACKGROUND: Mining high-throughput screening (HTS) assays is key for enhancing decisions in the area of drug repositioning and drug discovery. However, many challenges are encountered in the process of developing suitable and accurate methods for extracting useful information from these assays. Virt...

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Detalles Bibliográficos
Autores principales: Soufan, Othman, Ba-Alawi, Wail, Afeef, Moataz, Essack, Magbubah, Kalnis, Panos, Bajic, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105261/
https://www.ncbi.nlm.nih.gov/pubmed/27895719
http://dx.doi.org/10.1186/s13321-016-0177-8