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Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels

BACKGROUND: The leading cause of death among the obese population is heart failure and stroke prompted by structural and functional changes in the heart. The molecular mechanisms that underlie obesity-related cardiac remodeling are complex, and include hemodynamic and metabolic alterations that ulti...

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Detalles Bibliográficos
Autores principales: Lucas, Elisa, Vila-Bedmar, Rocio, Arcones, Alba C., Cruces-Sande, Marta, Cachofeiro, Victoria, Mayor, Federico, Murga, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105284/
https://www.ncbi.nlm.nih.gov/pubmed/27832814
http://dx.doi.org/10.1186/s12933-016-0474-6